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Symbol
Name
ID

Kl
klotho
MGI:1101771

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Premature coronary artery atherosclerosis	Hypertension	Sudden cardiac death	Myocardial infarction
Disease(s) Associated with KL
coronary artery disease

Mouse Phenotypes

abnormal aorta wall morphology

calcified aorta

arteriosclerosis

calcified artery

abnormal heart morphology

calcified mitral valve annulus

abnormal heart valve morphology

calcified aortic valve annulus

abnormal cardiovascular system physiology

abnormal blood circulation

hemorrhage

decreased heart rate

prolonged RR interval

abnormal sinoatrial node conduction

abnormal blood vessel physiology

Availability

Mouse Genotype

Kl^ecalc1/Kl^ecalc1

Kl^kl/Kl^kl

Kl^m1Anu/Kl^m1Anu

Kl^tm2Yin/Kl^tm2Yin

Kl^kl/Kl⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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